Many common household products contain chemicals that, when inhaled, produce a
drunken-like state. According to a recent HHS survey, approximately one out of five
eighth-graders reported using inhalants to get high at least once in their lives.
Most inhalants are extremely toxic to the body's organs. Inhalant use may cause neural
damage - leading to the loss of reasoning ability as well psychological and social
problems. Significant damage to the liver and kidneys may also occur. Some inhalants may
cause sudden death due to heartbeat irregularities.
Users of inhalants may have a sense of lightheadedness and experience vivid fantasies.
Long-term users often lose weight have nosebleeds, mouth sores, and are irritable or
depressed. Nausea, vomiting and extreme salivation are common side effects. The table
below fists common household products that are used as inhalants.
||model airplane glue, other glues, special elements
||spray paint, hair spray, deodorant, air freshener
||dry cleaning fluid, spot remover, degreasers
||whipped cream aerosols
|Solvents and Gases
||nail polish remover, paint remover, correction fluid, lighter fluid
Inhalants can be broken down into three major categories-volatile solvents, nitrites,
Volatile solvents are either gases, such as butane gas fumes, or liquids, such as
gasoline or paint thinner, that vaporize at room temperature. Since the 1950s, the number
of common products that contain volatile solvents has increased significantly. Besides
gasoline and paint thinner, products with volatile solvents include spray paint, paint and
wax removers, hair spray, adroitness, air fresheners, cigarette lighter fuels, analgesic
sprays, and propellant gases used in aerosols such as whipped cream dispensers.
Volatile solvents produce a quick form of intoxication-excitation followed by
drowsiness, disinhibition, staggering, lightheartedness, and agitation. Because many
inhalant products contain more than one volatile solvent, it is difficult to clearly
identify in humans the specific chemical responsible for subsequent brain or nerve damage
Some volatile solvents are inhaled by abusers because of the effects produced not by
the product's primary ingredient but by propellant gases, like those used in aerosols such
as hair spray or spray paint. Other volatile solvents found in aerosol products such as
gold and silver spray paint are sniffed not because of the effects from propellant gases
but because of the psychoactive effects caused by the specific solvents necessary to
suspend these metallic paints in the spray.
Nitrites historically have been used by certain groups, largely gay men, to enhance
sexual experience and pleasure. Often called "poppers' or "rush," some
nitrite products are sold as room odorizers. But use of nitrites has fallen off
dramatically in recent years. This may be partly because products containing butyl,
propyl, and certain other nitrites were banned in 1991, although products using chemical
variants of the banned substances are still sold.
For the past 13 years, NIDA's Monitoring the Future survey has adjusted for the
underreporting of nitrite use, recognizing that many survey respondents did not include
information about nitrite use when answering survey questions about inhalant abuse. That's
because most respondents fail to consider the use of nitrites as a form of inhalant abuse,
unless prompted with specific questions mentioning "poppers, rush," or other
nitrite-specific references, researchers say.
Some observers now believe that adjusting inhalant abuse survey results to combine
nitrite use with volatile solvent use can lead to mistaken conclusions when viewing
consolidated data over several years. That's because nitrite use is declining while
volatile solvent use has been on the rise for a number of years. "In combining
solvents with nitrites and then adjusting the data, it appears that inhalant use has not
changed over the past 16 years when, in fact, solvent use has steadily increased for a
decade and a half and just now may be leveling off," says Dr. Fred Beauvais, a
psychologist and NIDA-funded researcher at the Tri-Ethnic Center for Prevention Research
at Colorado State University at Fort Collins (see figure).
Because the current inhalant profile lumping nitrites with volatile solvents leads to
misleading data and inferences, many researchers believe that a scientific description of
inhalant abuse should distinguish abuse of volatile substances from abuse of nitrites and
Within the other major category of inhalants, the anesthetics, the principal substance
of abuse is nitrous oxide. A colorless, sweet-tasting gas used by doctors and dentists for
general anesthesia, nitrous oxide is called "laughing gas" because it often
induces a state of giggling and laughter. Recent anecdotal reports indicate that nitrous
oxide is being sold illicitly to teenagers and young adults at outdoor events such as rock
concerts and on the street. Nitrous oxide often is sold in large balloons from which the
gas is released and inhaled for its mind-altering effects.
But nitrous oxide is no laughing matter. Inhaling the gas may deplete the body of
oxygen and can result in death; prolonged use can result in peripheral nerve damage.
|Airplane Glue |
|Rubber Cement |
|Polyvinylchloride (PVC) Cement |
|Spray Paint |
|Hair Spray |
|Deodorant, Air Freshener |
Solvents and Gases
|Nail Polish Remover |
|Paint Remover |
|Paint Thinner |
|Typing Correction Fluid and Thinner |
|Fuel Gas |
|Cigarette Lighter Fluid |
|Dry Cleaning Fluid |
|Spot Remover |
Dessert Topping Sprays
|Whipped Cream, Whippets |
Nitrites and Anesthetics
Nitrite Room Odorizers
|"Poppers" and "Rush" |
[Adapted from Inhalant Abuse: A Volatile Research Agenda, NIDA
Research Monograph 129, 1992.]
Although no central system exists in the United States for reporting deaths and
injuries from abusing inhalants, several studies have documented the dangers associated
with inhalant abuse. A study by Dr. James C. Garriott, the chief toxicologist in San
Antonio and Bexar County, Texas, examined all deaths in the county between 1982 and 1988
that were attributed to inhalant abuse. Most of the 39 inhalant-related deaths involved
teenagers, with 21 deaths occurring among people less than 20 years old. Deaths of males
outnumbered those of females 34 to 5. Many of the abusers met with a violent death
possibly related to but not directly caused by the use of volatile solvents. Eleven deaths
were caused by suicide (10 by hanging), 9 by homicide, and 10 by accident, including
falls, auto accidents, and overdoses.
Most of those people who died in Bexar County had used toluene-containing products,
such as spray paints and lacquers, Dr. Garriott reported. The next most frequent cause of
death in the Texas study was the use of a combination of chemicals found in typewriter
correction fluids and other solvents. Other abused substances that resulted in death
included gasoline, nitrous oxide, and refrigerants, such as fluorocarbons (Freon). Freon
now has been replaced with butane or propane products in most aerosols.
By starving the body of oxygen or forcing
the heart to beat more rapidly and erratically,
inhalants can kill sniffers
As reported in the Texas study, the solvent toluene, a common component of many paints,
lacquers, glues, inks, and cleaning fluids, is identified frequently in inhalant abuse
deaths and injuries. A 1986 study of 20 chronic abusers of toluene-containing spray paints
found that after one month of abstinence from sniffing the paint, 65 percent of the
abusers had damage to the nervous system. Such damage can lead to impaired perception,
reasoning, and memory, as well as defective muscular coordination and, eventually,
In England, where national statistics on inhalant deaths are recorded, the largest
number of deaths in 1991 resulted from exposure to butane and propane, which are used as
fuels or propellants. Many researchers believe that abuse of butane, which is used in
cigarette lighters, is on the increase in the United States. NIDA's Dr. Sharp says,
"It's hard to tell whether this is a passing fancy or whether some youthful abusers
actually like to get dizzy on the butane and propane gases."
A recent report of this particular inhalant problem in the Cincinnati region indicates
that butane gas is the cause of enough deaths to foster national concern about the abuse
of fuel gases, whether or not it is a passing form of inhalant abuse, Dr. Sharp says. He
notes that "sniffers seem to go out of their way to get their favorite product."
For instance, in certain parts of the country, "Texas 'shoe-shine' [a shoe-shining
spray containing toluene] and silver or gold spray paints are local or current
favorites," he says. Since the banishing of fluorocarbons, the most common sniffing
death hazards among students in the United States probably are due to butane and propane,
Dr. Beauvais says. "Doctors and emergency room staffs need to be aware that the
profile of the teenager who inhales volatile solvents is not limited to the ethnic lower
socioeconomic classes," he cautions. "Many sources lead us to believe that abuse
of these readily available inhalants has reached epidemic proportions, indicating an
urgent need for preventive efforts directed at teenagers and their parents with emphasis
on the risk of sudden sniffing death."
One possible reason for the increased use of volatile solvents is that more girls are
joining boys in sniffing solvents. "The rates of solvent use for males and females
have been converging over the past 20 years," Dr. Beauvais says. Recent studies in
New York State and Texas report that males are using solvents at only slightly higher
rates than females are. Among Native Americans, whose solvent abuse rates are the highest
of any ethnic group, lifetime prevalence rates for males and females were nearly
identical, according to 1991 NIDA data.
There is a public perception that inhalant abuse is more common
among Hispanic youth than among other ethnic groups. However, recent surveys have not
found high rates of abuse by Hispanics in all geographic areas, Dr. Beauvais points out.
"It appears that rates for Hispanics may be related to socioeconomic
conditions," he says. "As those conditions vary so will the levels of solvent
use. Hispanic youths in poor barrio environments may use solvents heavily, but Hispanic
youths in less stressful environments do not."
In fact, inhalant abuse shows an episodic pattern, with short-term abuse outbreaks
developing in a particular school or region as a specific inhalant practice or product
becomes popular in a fashion typical of teenage fads. This episodic pattern can be
reflected in survey results and can overstate the magnitude of what is a continually
fluctuating level of abuse, says Dr. Beauvais.
Inhalant abuse came to public attention in the 1950's when the news media reported that
young people who were seeking a cheap "high" were sniffing glue. The term
"glue sniffing" is still widely used, often to include inhalation of a broad
range of common products besides glue, notes Dr. Charles W. Sharp of NIDA's Division of
With so many substances lumped together as inhalants, research data describing
frequency and trends of inhalant abuse are uneven and sometimes contradictory. However,
evidence indicates that inhalant abuse is more common among all socioeconomic levels of
American youth than is typically recognized by parents and the public. For instance,
NIDA's Monitoring the Future survey shows that in 1993, one in every five 8th graders, or
19.4 percent, used an inhalant in his or her lifetime.
Inhalants were used by equally high percentages of 10th and 12th graders, according to
the NIDA survey. Lifetime inhalant use among 12th graders, which had increased steadily
for most of the 1980s, leveled off somewhat at 17.4 percent in 1993. Also, 17.5 percent of
10th graders reported lifetime inhalant use in 1993.
Inhalants are most commonly used by adolescents in their early teens, with usage
dropping off as students grow older. For example, while 5.4 percent of 8th graders
reported using inhalants within the past 30 days, known as "current" use, only
2.5 percent of seniors reported current use of inhalants.
A major roadblock to recognizing the size of the inhalant problem is the ready
availability of products that are inhaled. Inhalants are cheap and can be purchased
legally in retail stores in a variety of seemingly harmless products. As a result,
adolescents who sniff inhalants to get high don't face the drug procurement obstacles that
confront abusers of other drugs.
Inhalant abuse also appears to be a problem worldwide according to research data
presented at a recent NIDA technical review, "Epidemiology of Inhalant Abuse: An
International Perspective." According to Nicholas Kozel, of NIDA's Division of
Epidemiology and Prevention Research, low price and easy availability and access make
inhalants as problematic in Africa, Asia and Latin America as it is in the United States.
Trends in Lifetime Use of Inhalants, Inhalants Adjusted, and Nitrites by
High School Seniors, 1979-1993
In surveys of drug use, the category "Inhalants
Adjusted" includes the use of nitrites and volatile solvents. Some researchers
believe this category leads to misleading conclusions about trends in the prevalence of
inhalant use. For instance, the "adjusted" figures from NIDA's 1993 Monitoring
the Future survey indicate that inhalant use by high school seniors has been fairly stable
since 1979. But nitrite use has gone down dramatically during that period. The true
picture of inhalant use, say some observers, is the category "inhalants", which
does not include nitrites and which has steadily increased for several years before
Inhalant abusers typically use other drugs as well. "Children as young as 4th
graders who begin to use volatile solvents also will start experimenting with other drugs,
usually alcohol and marijuana," says Dr. Beauvais. "Adolescent solvent abusers
are typically polydrug users and are prone to use whatever is available, although they do
show a preference for solvents." However, solvent abuse often is held in low regard
by older adolescents, who may consider it unsophisticated, a "kid" habit, he
Not only juveniles are abusing inhalants. Current reports indicate that college age and
older adults are the primary abusers of butane and nitrous oxide.
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|source: NIDA Research Report - Inhalant
Abuse, NIH Publication No. 94-3818